Статья из платной подписки на NHD ( Natural Health Dossier) об эффективном влиянии препарата из
экстракта семян винограда на раковые клетки.Tuesday, August 21, 2012
Natural Compound Kills Cancer, Leaves Healthy Cells Unharmed
For thousands of years, people have harvested grapes. Think of the ancient Romans… the Greeks. But not just because they taste great. As Hippocrates – the Father of Medicine – noted, these gem-like fruits have miraculous healing properties.
And modern science has proven him right. Scientists have discovered more than a hundred biologically-active compounds in grapes. And while the flesh might be the sweetest and tastiest part, the skin and seeds have the greatest nutritional value.
In fact, research shows that nutrients extracted from grape seeds can provide powerful protection against many forms of cancer. That includes stomach, breast, colon, lung, skin, and prostate cancer.
Here’s how it works…
Selective cytotoxicity is the most promising area of cancer research. It simply means that a compound can kill cancer cells, while leaving healthy cells unharmed. Unfortunately, chemotherapy drugs fail to meet this standard. But there are natural compounds that can wipe out cancer cells and leave healthy cells to thrive.
Xianglin Shi, PhD from the University of Kentucky is a researcher who looks for compounds like this. “What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone,” says Dr. Shi.
And he just may have found it in the seeds of a grape…
According to the journal Clinical Cancer Research, Shi exposed and treated leukemia cancer cells with a commercially available grape seed extract (GSE) in different doses. 1He found that grape seed extract caused cancer cells to self-destruct. The higher the dose, the more cancer cells died.
2And even better… GSE killed 76 percent of cancer cells within 24 hours, while leaving the healthy cells completely unharmed.
Dr. Shi says these results might be enough to start using agents such as GSE to prevent and treat cancer.
Another study, published in the journal Carcinogenesis, confirms his findings.3
Rajesh Agarwal, PhD conducted the study on mice with mouth or nasal cavity cancer. The mice received GSE in their feed. And just like in the previous study, cancer cells died. The healthy cells remained unharmed. The mice also showed no toxicity to GSE.
“Cancer cells have a lot of defective pathways,” said Dr. Agarwal. “And they are very vulnerable if you target those pathways.”
That’s just what the GSE did. But how?
Researchers in both studies found that the anti-cancer effect is due to GSE’s activation of a protein in our body called JNK. Once activated, JNK damages the DNA of cancer cells. This causes them to self-destruct. It does not have this effect on healthy cells.4
In cancer treatment, cell suicide is important. But keeping healthy cells alive is just as vital. Chemotherapy doesn’t exclusively target cancer cells. It damages and destroys healthy cells too. Perhaps even worse, according to a recent study in Nature Medicine5 (among others), chemotherapy can actually cause cancer.
These studies on grape seed extract are great news for anyone who wants to treat and prevent cancer. But it doesn’t mean you should fill your grocery cart with grapes. The grapes that Hippocrates called “medicine” were very different from the grapes you’ll find in the store today. Most commercial grapes – especially the green seedless variety – were bred to be sweet and juicy. They are full of sugar and have little nutritional value.
If you do enjoy grapes, choose smaller varieties with red or purple skin. And always buy organic. Conventional grapes are loaded with pesticides.
But for the greatest nutritional benefit, consider taking a high quality grape seed extract supplement. They usually come in capsule form. And they can be easily found online. Also, while grape seed oil might be good for cooking, it does not contain the anti-cancer compounds found in the extract. So it should not be used as a substitute.
GSE is perfectly safe to consume. And research proves that it kills cancerous cells. It’s a win-win. It might just keep cancer – and chemo – at bay.
References:
1http://abcnews.go.com/Health/Healthday/story?id=6557928&page=1#.UCnC8hwdCdw
2http://www.ncbi.nlm.nih.gov/pubmed/19118041
3http://www.ncbi.nlm.nih.gov/pubmed/22266465
4http://www.ncbi.nlm.nih.gov/pubmed/20581839
5http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.2890.html
http://naturalhealthdossier.com/2012/08/natural-compound-kills-cancer-leaves-healthy-cells-unharmed/
Grape Seed Extract
Viva la France! Renowned for its accomplished chefs, crusty*
bread, rich cheeses and infamous wines, France is considered the*
culinary center of the world. The French are also legendary for*
their good heart health, despite their consumption of decadently*
rich foods. It’s no surprise that researchers looked for an*
explanation to this conflicting “French Paradox”. What they*
found was a surprising habit of red wine accompanying*
most French meals. The wine led them to the grape and*
the grape to the scientist who discovered its amazing*
properties, France’s own Jacques Masquelier.*
Dr. Masquelier’s work extracting compounds from plants started with*
peanuts in 1948 before moving on to grapes. He found that when he*
fed laboratory rats the new substance, it was absorbed rather quickly,*
particularly influencing blood vessels and doubling their strength in*
a matter of hours. Research was laborious and painstakingly slow. It*
took Masquelier more than two decades before he completed his work*
and eventually patented two processes of extraction, one from pine bark, the second*
from grape seeds. Masquelier himself learned that grape seed extract was the more powerful of*
the two. Although he called the active compounds “pycnogenols”, the name was later changed*
to more accurately describe the collective properties of procyanidolic oligomers or PCOs, for short. These PCOs can*
be found in green tea, fruits and vegetables but look to grape seeds as the richest source.*
Thanks to Masquelier, we can reap the same healthy benefits as the French. Grape seed extract (GSE) is available as a*
supplement with a standardized PCO content. GSE works most of its wonder as an antioxidant, protecting cells, tissues and*
organs from free radicals or oxidative damage. Oxidation is linked to premature aging and age-related disorders such as*
arthritis, cancer and heart disease. The simplest illustration is to observe a cut apple, exposed to the air. Oxygen breaks down*
the connective tissues in the apple, turning it brown and causing it to slowly decay. The same process occurs in a much more*
complicated way in our own bodies. Oxygen, while essential to life, is also our most common free radical. Compared to other*
antioxidants, GSE is 50 times more potent than vitamin C and 20 times more potent than vitamin E. What’s more, GSE stays*
in the blood longer than either antioxidant (up to 72 hours), giving you sustained antioxidant power against free radicals!
How can grape seed extract benefit you? The following Q&A format will make it easy for you to find the information you*
need quickly so you can start GSE working for you!
Why do I need GSE if PCOs are found in fruits and veggies?
Fair question! Unfortunately, statistics reveal that Americans on the average only get 1.5 of their vegetable portion and*
1 of their fruit. And unless you’re eating organic, you’ll need antioxidants just to detoxify the chemically*
challenged produce you do buy! Seriously, GSE contains a trio of PCOs that work quite effectively*
together and yet have distinct characteristics of their own (defined by the number of their chemical*
units). Simply put, collectively they fight against viruses, cancers and inflammation, stabilize blood*
pressure and strengthen blood vessels, to name a few! Like our friend, the apple, your exposure*
to oxygen is a two-edged sword with decay going on the outside where you can see it—in the*
forms of wrinkles and sun spots—and on the inside where you cannot.*
Continuedby Margy Squires
https://www.e-tyh.com/cscart/Health_Library_PDFs/Grapeseed_Extract.pdf